PURPOSE: Complete androgen blockade (CAB) does not prolong overall survival (OS) in patients with castration refractory prostate cancer (CRPC).Although there is variable clinical benefit with second-line hormone manipulation, we do not know which patients might benefit the most.OBJECTIVES: To identify clinical predictors of benefit of complete andr

Depression, an emotion regulation disorder, is a prevalent mental illness in the world.Meanwhile, traditional Chinese medicine (TCM) has been increasingly regarded as a promising and effective alternative therapy approach for patients with depression.Despite many years of Biscuits research on depression, the current understanding of the pathologica

Abstract The role of iron in the two major sites of adaptive thermogenesis, namely the beige inguinal (iWAT) and brown adipose tissues (BAT) has not been fully understood yet.Body iron levels and distribution is controlled by the iron regulatory peptide hepcidin.Here, we explored Covers iron homeostasis and thermogenic activity in brown and beige f

IntroductionTransition from pediatric to adult healthcare is a multifaceted and consequential process with important health implications for youth.Although research on transition has grown significantly, research on transition for patients living with an inborn error of immunity (IEI) is scarce.We undertook a qualitative study to better understand

Salinity stress is one of the factors that threatens the growth and yield of corn.The effects of silicon or nanosilicon on salinity alleviation have been reported in some plants.The effects of foliar application of silicon (inorganic and nanopatricle) on mitigation of the effects of salinity stress on some photosynthetic and biochemical parameters